Try it and do research.

Psilocybin works specifically for the (thankfully) rare cluster headaches. They are so painful that most people commit suicide. 

As far as cannabis, it is a useful tool to alleviate migraine symptoms, or even prevent them.

Trial and error, for everyone, is unfortunately part of the process. Don’t get turned off by cannabis if you smoke a random joint and it doesnt help. There are many other methods.

– in general, smoking weed is the fastest way to your bloodstream. The fastest working, yet the most inefficient. It works the fastest, but has the shortest duration. Luckily, some people feel all the relief that they need from smoking and/or vaping, and they are the fortunate few. . . If you do an edible or tincture, some like the smoke in the meantime because it helps take the edge off a bit and gets your cannabinoids to work.

– edibles are a lot longer lasting. They will typically take longer to feel (as little as 15 minutes with the lipid fat encapsulated edibles to an hour or more for the typical ones). However, their duration is much longer. I’ve had edibles work well from 830 am to 5 PM… cannabis. when combusted or inhaled using convection (vaping) are Delta-9 hydroxy THC. Edibles become a much heavier, more body-fulfilling and even psychedelic Delta-11 hydroxy THC. This Delta-11 is much more appropriate for pain relief, insomnia relief, anxiety relief, nausea, the list goes on.

– tinctures are used sublingually. As in, you drop the liquid underneath your tongue for about 10 seconds, then swallow. This allows for a fuller, quicker onset and more full spectrum bloodstream dispersion. These (as well as the bud, edibles and vapes, etc) come in not only THC mixtures, but 1:1 ratios of THC:CBD, and also higher CBD ratios. The truth is, CBD is a great cannabinoid alone, but you need at least a little bit of THC to help the entourage effect of all of the other cannabinoids.

– there are topicals of different ratios as well. Pain salves, rubs, creams, sprays. Little to no psychoactivity. 

Any more question just ask. Been doing this for over 4 years.